What Effect Does Electronic Cigarette Smoking Have On Pregnant Women?

E-cigarette smoking by pregnant women has adverse effects on the fetus, especially during the development of various important organs of the fetus in the first four months of pregnancy. Nicotine in e-cigarettes may lead to abnormal fetal development and even abnormal fetus. Therefore, pregnant women must quit smoking in advance, at least during pregnancy preparation. E-cigarettes are the same.

There are many experiments to study the effect of nicotine on the fetus. The results show that the continuous action of nicotine during pregnancy in mice will directly affect the development of the fetus, including cell damage, increased inflammation, increased oxidative pressure, and damage the ability of cell replication. Experiments in mice have indeed shown the malignant damage of nicotine to the fetus, but the physiological differences between species will bring many problems. Therefore, scientists have also tried to study its impact on the human fetus.

Therefore, scientists conducted experiments on the effects of nicotine on human embryonic stem cells, and found that nicotine could inhibit the growth and differentiation of human embryonic stem cells, and the genes related to differentiation were significantly down regulated in the early stage, especially the genes related to blood and musculoskeletal. In addition, microRNAs with gene regulation function are also affected, and multiple basic signal pathways are also disturbed.

After human embryonic stem cells were exposed to nicotine for 6 days, it was found that the genes related to cell survival were significantly reduced. Originally, the expression of these genes could protect cells from metal toxicity and superoxide stress. Without these abilities, the viability of cells would be significantly down regulated, which means that the growth and development ability of embryos in the early stage was negatively affected by nicotine; In addition, the expression of genes related to cell cycle is also abnormal. Embryonic stem cells that should have completed differentiation do not normally produce precursor cells, which may lead to the delay of fetal tissue development.

According to the results of these experiments, nicotine also has a great impact on the human fetus.

To sum up, pregnant women smoking e-cigarettes will affect the development ability of the fetus, that is, the development will be delayed. Therefore, in this case, pregnant women will quit smoking in order to give birth to a healthy baby. Even e-cigarettes need to be quit.