Use electronic cigarettes to reduce the risk of oral diseases

A recent research paper released by the American Chemical Society pointed out that propylene glycol, the main component of the electronic fuming liquid, can inhibit oral bacteria and the inflammation induced by it, and smokers can switch to electronic cigarettes, which may effectively reduce the risk of oral diseases such as oral cancer.

The study used liquid chromatography to quantitatively study the AP site
The American Chemical Society is one of the largest scientific organizations in the world, authorized by the United States Congress, and has more than 150000 members in 140 countries. Propylene glycol is mainly used to enhance the stability of electronic fuming liquid.

The paper was published in the authoritative journal Toxicological Chemical Research. The picture is a screenshot of the official website of the American Chemical Society

Researchers found that propylene glycol has certain antibacterial effect through a group of animal experiments. Research shows that in a confined space, propylene glycol with a concentration of 0.5 ppm can quickly sterilize Streptococcus pneumoniae, influenza virus and other microorganisms. With the increasing concentration, propylene glycol can also inhibit the growth of various pathogenic bacteria such as Escherichia coli and Streptococcus mutans. Among them, Streptococcus mutans is an important factor leading to tooth decay, and Escherichia coli can cause gastrointestinal infection. In order to further explore the impact of e-cigarettes on the human oral environment, the study selected 30 smokers and 30 e-cigarettes users, and for the first time adopted the method of detecting the AP site (apyrimidine site) of human oral cells - DNA damage will form the AP site, the higher the level of AP site, the more serious the DNA damage, the more likely to cause gene mutation and cancer.

The official website of the Journal of Dental Research published the research paper Electronic Cigarette and Oral Health, which was jointly carried out by dental experts from the University of Newcastle in the United Kingdom and the University of California in the United States

The results showed that the level of AP sites in oral cell DNA of electronic cigarette users was 3.3/107nts, far lower than that of smokers' 5.7/107nts. The difference is particularly significant in the 30-50 age group. The level of AP sites (3.0/107nts) of electronic cigarette users in this group is twice lower than that of smokers (6.0/107nts). Does this mean that the oral environment will be improved after smokers switch to electronic cigarettes? The world-famous SCI journal Journal of Dental Research published relevant research papers in 2021. The results showed that the periodontal environment of smokers with oral diseases would be improved after they switched to electronic cigarettes, regardless of whether the dentist provided treatment services or not.
"There are more than 700 kinds of bacteria in the mouth, and most of the patients with oral diseases are smokers." British dental expert R Holliday said: "The comparative study of e-cigarettes and cigarettes is very useful to us. I hope that dentists can put aside their prejudice and learn more about the positive impact of e-cigarettes on the oral health of smokers with diseases."